Cisplatin or carboplatin

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August undefined, 2024

WebApr 15, 2024 · A 52-year-old man developed mucositis and weight loss during treatment with cisplatin for high-grade squamous cell carcinoma (SCC) of the left nasal cavity arising from sinonasal inverted papilloma (IC). The man, who had a history of long-term tobacco …

Cisplatin nephrotoxicity - UpToDate

WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and... WebDec 7, 2024 · In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. Methods A total of 1305 patients with previously untreated ES-SCLC were included in this study. Data from five … cumberland rowan college south jersey

Pembrolizumab or Placebo Plus Etoposide and …

WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … WebMar 30, 2024 · FDA approves durvalumab for extensive-stage small cell lung cancer On March 27, 2024, the Food and Drug Administration approved durvalumab (IMFINZI, AstraZeneca) in combination with etoposide and... WebOct 20, 2024 · Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years’ follow-up. … east telly

Carboplatin- or cisplatin-based chemotherapy in first-line …

Pembrolizumab plus Chemotherapy in Metastatic …

WebCisplatin and carboplatin based combinations are not used as an initial therapy. The indications for these two drugs are primary resistant malignant lymphoma and multiple myeloma, or relapses of these diseases not responding to conventional therapy. WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment.4Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and nephrotoxicity, but similarly it increases the risk of myelosuppression. east tennessee atv elizabethton tnWebDec 7, 2024 · In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. Methods A total of 1305 patients with previously untreated ES-SCLC were included in this study. Data from five trials were collected from the public database Project Data Sphere. east tennessee auto sales and leasing

"WebApr 4, 2024 · Carboplatin belongs to a class of medications known as platinum-containing compounds. It works by stopping or slowing the growth of cancer cells. Carboplatin is used in adults in combination with other cancer treatments to treat ovarian cancer. " - Cisplatin or carboplatin

Cisplatin or carboplatin

Carboplatin - Drug Information - Chemocare

WebApr 10, 2024 · Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, … WebMay 10, 2012 · Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data. Our meta-analysis of individual patient data suggests no differences in efficacy between cisplatin …

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WebOct 14, 2024 · The key difference between carboplatin and cisplatin is that carboplatin shows less consistent survival advantages, whereas cisplatin shows more consistent survival advantages in meta-analyses of … WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and ...

WebChemoradiotherapy with paclitaxel liposome plus cisplatin for locally advanced esophageal squamous cell carcinoma: A retrospective analysis ... (TF), and paclitaxel and carboplatin (TC) schemes, which did not show significant survival benefits. 7 , 10 , 12 Currently, paclitaxel‐based chemotherapy is a concurrent regimen commonly used in clinics. WebIncluded trials evaluated etoposide, mitomycin with vindesine or vinblastine, cisplatin or carboplatin with paclitaxel, docetaxel, gemcitabine, or cisplatin and carboplatin in combination with tirapazamine. Doses varied between trials. The median number of …

WebPembrolizumab was approved for use in combination with platinum and fluorouracil (FU) for all patients and as a single agent for patients whose tumors express PD‑L1 (Combined Positive Score [CPS]... WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment. 4 Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and …

WebNov 5, 2024 · The primary objective is to assess the pathological complete response rate (ypT0) in each cohort and independently of a combination therapy with neoadjuvant durvalumab and chemotherapy (Gemcitabine/Cisplatin) before surgery in patients with high-risk, localized, non-metastatic urothelial carcinomas of the upper tract.Secondary …

WebCarboplatin / pharmacology Cisplatin / metabolism Cisplatin / pharmacology* Cisplatin / therapeutic use DNA / drug effects Drug Resistance / genetics Gene Expression Regulation, Neoplastic / drug effects ... east tennessee acreage for saleWebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the … cumberland rslWebBoth chemo drugs are hard on the bone marrow & kidneys--they both cause neuropathy & can cause hearing loss. The carboplatin is a little more gentle on the kidneys so you must have good kidneys. For sure, you should drink a lot of water before & after chemo … east tennessee baptist association newport tnWebJul 19, 2016 · Carboplatin yielded comparable results to cisplatin in concurrent chemo-radiation for locally advanced cervical cancer. In addition, carboplatin was associated with a better compliance rate and was associated with less of anemia, neutropenia and nephrotoxicity. Peer Review reports Backgrounds east tennessee atv elizabethtonWebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the toxicity of carboplatin was not affected by decreasing the expression of MATE1 ... cumberland rubys pantryWebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … east tennessee autism societyWebCisplatin and carboplatin can affect the kidneys. Giving plenty of fluids can help reduce this risk. These drugs can also affect hearing. Your child’s doctor may order hearing tests (audiograms) during or after treatment. Vincristine and … cumberland royal infirmary hospital