Eg7 thymoma
WebFeb 8, 2013 · Systemic administration of resveratrol suppressed tumor growth in EG7 thymoma-bearing mice in an IDO-dependent manner. Taken together, resveratrol not only regulates immune response through the regulation of IDO in a JAK/STAT1- and PKCδ-dependent manner, but also modulates the IDO-mediated immune tolerance in EG7 … WebExperimental protocol and time schedule for subcutaneous tumor injection of syngeneic, ovalbumin-expressing mouse thymoma cells (3 × 10⁵ E.G7-OVA cells in 50 µl PBS) into the right hind leg ...
Eg7 thymoma
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WebJun 1, 2001 · EG7 is a derivative of the H-2 b thymoma EL4, which was transfected with cDNA encoding full-length chicken OVA and displays the immunodominant epitope of … WebMar 7, 2024 · A thymoma is a rare type of tumor of the thymus gland. The thymus is a gland located in the anterior mediastinum (the area between the two lungs and the sternum in …
WebOct 1, 2024 · EL4 is a cell line (T-cell thymoma) and EG7 is a clone of EL4 cells that is transfected with cDNA gene coding for chicken egg ovalbumin (OVA), and upon transfection, EG7 cells express ova in a membranous form. 8 Both EL4 and EG7 cells express only class-I molecules but not class-II molecules. WebArticle Snippet: The murine thymoma cell line EG7 (EL4-OVA: EL-4 thymoma cells transfected with chicken albumin cDNA) was obtained from ATCC (CRL-2113). …
WebOur anti-CD27 candidate induces a significant anti-tumor activity in the EG7 thymoma model. We have also demonstrated the anti-tumor efficacy of this lead candidate in Raji cells implanted in Scid mice. Preliminary experiments performed in human CD27 KI mice have demonstrated a long half-life of our antibody at different concentrations. WebAug 19, 2007 · To determine which TLR might control the immune response against dying tumor cells, we fed dying ovalbumin (OVA)-expressing EG7 mouse thymoma cells to bone marrow–derived DCs (BM-DCs) that were ...
WebOct 1, 2024 · EL4 is a cell line (T-cell thymoma) and EG7 is a clone of EL4 cells that is transfected with cDNA gene coding for chicken egg ovalbumin (OVA), and upon transfection, EG7 cells express ova in a membranous form. 8 Both EL4 and EG7 cells express only class-I molecules but not class-II molecules. All cell lines were purchased …
WebThe E.G7-OVA is a mouse lymphoma cell line derived by the electroporation of EL4 cells with a plasmid which carries a complete copy of chicken ovalbumin (OVA) mRNA. These … how to sign up for library cardWebConclusions: Our data suggest that AdVIL-6 -transfected DC-stimulated CD8 (+) T cells with potent cytotoxicity and survival advantage may serve as an effective adoptive CD8 (+) T … nouryon project thorWebCRL-2113 ™. E.G7-OVA [derivative of EL4] T lymphoblasts are T lymphoblasts derived in 1988 from the C57BL/6 (H-2 b) mouse lymphoma cell line EL4 ( ATCC TIB-39 ). E.G7 … how to sign up for link cardWebFeb 9, 2012 · OVA-pulsed DCs reduced the population of CSFE-stained OVA-expressing EG7 tumor cells compared to non-pulsed DCs, and OVA-expressing EG7 tumor cells were significantly lysed in FAP-treated DCs... nouryon pronunciationWebMar 20, 2008 · Most EG7-mYFP tumor cells were rapidly eliminated after transfer of activated OT-I CD8 + T cells but not after transfer of naive OT-I CD8 + T cells. Scale bars: 100 μm. CTLs enhance their effector functions upon antigen recognition in … nouryon polymer chemistryWebnoma, the EG7 thymoma, and the NXS2 neuroblastoma. Although the clearance of these tumors is dependent on CD8 T cells, it was the a4-1BB-mIgG2a that was most potent in control of all three tumors, whereas the a4-1BB-mIgG1 had minimal activity as a monotherapy. This led the authors to ask whether a4-1BB-mIgG2a induced cell … nouryon radnor addressWebOct 3, 2024 · In the EG7 thymoma model with the highest level of P2X7, we observed again that the P2X7-potentiating biologic had no effect on the early phase of tumor growth. However, as also observed in the … nouryon product data sheet